Welcome to KINAXO

Understanding how targeted drugs act is a key issue in any drug development program. To this end, KINAXO offers a unique technology platform which allows comprehensive analysis of signal transduction processes and their response to drug treatment. KINAXO thus reveals your drug's mode of action in biological samples and facilitates identification of biomarkers for patient stratification. KINAXO significantly supports decision making at various stages of the drug discovery process and enables prediction of a drug's therapeutic outcome, thus backing tailor-made therapy to increase the individual's therapeutic benefit and reduce the risk of unwanted side effects.

Make more confident decisions in drug discovery

KINAXO Cellular Target Profiling^® Determine your compound’s proteome-wide interactions		KinAffinity^® Evaluate your kinase inhibitor’s target spectrum on a kinome-wide basis		PhosphoScout^® Gain insights into your compound’s cellular mode of action
KINAXO Cellular Target Profiling^® determines a small molecules’ quantitative cellular target profile		KINAXO’s KinAffinity^® rapidly and efficiently profiles kinase inhibitors against any cell line or tissue		KINAXO’s quantitative phospho-proteomics technology comprehensively investigates drug effects at the signal transduction level

	KINAXO’s technology published in Nature Methods / Sharma et al., Nature Methods 2009, 6, 741-4
	KINAXO’s SubExtractor algorithm published in BMC / Klammer et al. BMC Bioinformatics 2010, 11:351
	KINAXO’s Sorafenib PhosphoScout^® Case Study / Tebbe et al., Poster SBS 2010